Tissue-type plasminogen activator

UniProt : P00750, UniProt ID: TPA_HUMAN,

Tissue-type plasminogen activator

Homo sapiens

MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIYQQHQSWLRPV
LRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCE
IDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCR
NPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWN
SMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCG
LRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQ
ERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCA
QESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQH
LLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQK
DVPGVYTKVTNYLDWIRDNMRP

The graphic displays domains and Protease cut sites on the protein sequence. Drag your mouse right/left over the graphic. Use the selection boxes on the right to select which annotations to view simultaneously. Combine annotation with multiple checkmarks.

InterPro Domain:
CutDB Proteolytic Event:
Protease:
MEROPS family:
Seq range: -
Cleavage position:
Cleavage residues:

Tissue-type plasminogen activator contains a PF00039 domain.

Tissue-type plasminogen activator contains a PF00089 domain.

Tissue-type plasminogen activator contains a PF00051 domain.

Tissue-type plasminogen activator contains a PF00051 domain.

Tissue-type plasminogen activator contains a PF00008 domain.

Tissue-type plasminogen activator is proteolytically cut by plasmin (S01.233) cleavage. PQFR-IKGG.

Tissue-type plasminogen activator is proteolytically cut by plasmin (S01.233) cleavage. PQFR-IKGG.

Tissue-type plasminogen activator is proteolytically cut by t-plasminogen activator (S01.232) cleavage. PQFR-IKGG.